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Rabbit Anti-Phospho-TCTP(Ser46)/RBITC Conjugated antibody (bs-3422R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3422R-RBITC
英文名稱 Rabbit Anti-Phospho-TCTP(Ser46)/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的磷酸化翻譯控制腫瘤蛋白抗體
別    名 Fortilin; Histamine-releasing factor; p02; p23; TPT1; translationally controlled tumor protein; tumor protein translationally-controlled 1; TCTP_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 腫瘤  細胞生物  免疫學  信號轉導  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human TCTP around the phosphorylation site of Ser46
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
TCTP is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Both human and mouse recombinant HRF proteins caused histamine release from human basophils of a subpopulation of donors (referenced from OMIM).

Function:
Involved in calcium binding and microtubule stabilization.

Subunit:
Interacts with STEAP3.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.

Similarity:
Belongs to the TCTP family.

Database links:

Entrez Gene: 7178 Human

Entrez Gene: 22070 Mouse

Entrez Gene: 116646 Rat

Omim: 600763 Human

SwissProt: P13693 Human

SwissProt: P63028 Mouse

SwissProt: P63029 Rat

Unigene: 374596 Human

Unigene: 296922 Mouse

Unigene: 297482 Mouse

Unigene: 36610 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

翻譯控制腫瘤蛋白最初發現于腫瘤組織,后來又從其他組織中相繼分離出來,是許多動物腫瘤細胞中存在的一類較豐富的蛋白,TCTP參與鈣離子結合和微管的穩定,是一類廣泛存在于動物、植物及酵母中的、在序列上高度保守且具有很高表達量的蛋白家族。
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