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Rabbit Anti-EN2/BF594 Conjugated antibody (bs-11552R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11552R-BF594
英文名稱 Rabbit Anti-EN2/BF594 Conjugated antibody
中文名稱 BF594標記的同源盒蛋白轉(zhuǎn)錄因子EN2抗體
別    名 AUTS 1; AUTS1; EN 2; Engrailed 2; Engrailed homeo box 2; Engrailed homeobox 2; Engrailed homolog 2; Engrailed2; Homeobox protein engrailed 2; Homeobox protein engrailed2; Hu En 2; HuEn2; MabEn; HME2_HUMAN; Homeobox protein engrailed-2; Homeobox protein en-2; Hu-En-2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  干細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EN2/Engrailed 2 (281-333aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008].

Function:
EN1 and EN2 encode homeodomain containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. EN2 may play a role in susceptibility to autism spectrum disorders.

Subcellular Location:
Nuclear.

DISEASE:
Note=Genetic variations in EN2 may be associated with susceptibility to autism.

Similarity:
Belongs to the engrailed homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 2020 Human

Entrez Gene: 13799 Mouse

Entrez Gene: EN2 Rat

Omim: 131310 Human

SwissProt: Q05917 Chicken

SwissProt: P19622 Human

SwissProt: P09066 Mouse

Unigene: 134989 Human

Unigene: 4298 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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