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phospho-FGFR3 (Y642) Recombinant Rabbit mAb (bsm-63304R)  
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產品編號 bsm-63304R
英文名稱 phospho-FGFR3 (Y642) Recombinant Rabbit mAb
中文名稱 磷酸化成纖維細胞生長因子受體3重組兔單抗
別    名 ACH; CD333; CEK2; FGFR3; Fibroblast growth factor receptor 3; HSFGFR3EX; Hydroxyaryl protein kinase; JTK4; Tyrosine kinase JTK 4.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 11G8
交叉反應 Human,Mouse
產品應用 WB=1:1000-1:2000,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 88 kDa
檢測分子量 88
性    狀 Liquid
免 疫 原 A synthesized peptide derived from human FGFR3 around the phosphorylation site of Y642: DL-pY-MI 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
保存條件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts.

SWISS:
P22607

Gene ID:
2261

成纖維細胞生長因子受體3也是酪氨酸激酶受體家族成員,在細胞有絲分裂的發生、血管新生、傷口愈合及腫瘤形成中起重要作用。FGFR3目前多用于腫瘤方面的研究。
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