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SEC23IP Rabbit pAb (bs-19615R)  
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產品編號 bs-19615R
英文名稱 SEC23IP Rabbit pAb
中文名稱 SEC23相互作用蛋白抗體
別    名 CDA II; CDAII; CDAN2; HEMPAS; Protein transport protein Sec23B; RP11-379J5.1; SC23B_HUMAN; Sec23 homolog B(S. cerevisiae); SEC23 related protein B; SEC23-like protein B; SEC23-related protein B; Sec23b; Transport protein SEC23B.  
研究領域 腫瘤  細胞生物  發育生物學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,Rabbit,Sheep (predicted: Human,Mouse,Cow,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 111 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEC23IP: 811-910/1000 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Function:
Plays a role in the organization of endoplasmic reticulum exit sites.

Subcellular Location:
Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum.

Tissue Specificity:
Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.

Similarity:
Belongs to the PA-PLA1 family.
Contains 1 DDHD domain.
Contains 1 SAM (sterile alpha motif) domain.

SWISS:
Q9Y6Y8

Gene ID:
11196

Database links:

Entrez Gene: 11196 Human

Entrez Gene: 207352 Mouse

Entrez Gene: 309010 Rat

SwissProt: Q9Y6Y8 Human

SwissProt: Q6NZC7 Mouse

Unigene: 435004 Human

Unigene: 667094 Human

Unigene: 297105 Mouse



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