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OSBPL2 Rabbit pAb (bs-17517R)  
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產品編號 bs-17517R
英文名稱 OSBPL2 Rabbit pAb
中文名稱 氧固醇結合蛋白樣2抗體
別    名 FLJ20223; KIAA0772; MGC4307; MGC8342; ORP2; OSBP related protein 2; Oxysterol binding protein like 2; Oxysterol binding protein related protein 2.  
研究領域 腫瘤  細胞生物  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 54 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OSBPL2: 361-460/480 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
This gene encodes a member of the oxysterol binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N terminal pleckstrin homology domain and a highly conserved C terminal OSBP like sterol binding domain, although some members contain only the sterol binding domain. This encoded protein contains only the sterol binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3 phosphate, but cannot bind to 25 hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

SWISS:
Q9H1P3

Gene ID:
9885

Database links:

Entrez Gene: 9885 Human

Entrez Gene: 228983 Mouse

Entrez Gene: 296461 Rat

Omim: 606731 Human

SwissProt: Q9H1P3 Human

SwissProt: Q8BX94 Mouse

Unigene: 473254 Human

Unigene: 253578 Mouse

Unigene: 12390 Rat



產品圖片
Sample: Pancreas (Mouse) Lysate at 40 ug Primary: Anti-OSBPL2 (bs-17517R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD
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