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TSPAN3 Rabbit pAb (bs-9412R)  
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產品編號 bs-9412R
英文名稱 TSPAN3 Rabbit pAb
中文名稱 四分子交聯體3/四旋蛋白3/四次跨膜蛋白3抗體
別    名 tetraspanin 3; tetraspanin TM4 A; TM4 A; TM4A; TM4SF8; transmembrane 4 superfamily member 8; TSPAN 3; TSPAN-3; TSPAN3; TSN3_HUMAN.  
研究領域 細胞生物  免疫學  信號轉導  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Zebrafish,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TSPAN3: 61-160/253 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 TSPAN3 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Two alternative transcripts encoding different isoforms have been described.

Function:
Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.

Subunit:
Interacts with claudin-11/CLDN11 and integrins.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

SWISS:
O60637

Gene ID:
10099

Database links:

Entrez Gene: 10099 Human

Entrez Gene: 56434 Mouse

Omim: 613134 Human

SwissProt: Q3SZR9 Cow

SwissProt: O60637 Human

SwissProt: Q9QY33 Mouse



產品圖片
Sample: spinal cord(mouse) Lysate at 40 ug Primary: Anti- TSPAN3 (bs-9412R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28kD Observed band size: 28 kD
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