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CXXC5 Rabbit pAb (bs-6890R)  
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產品編號 bs-6890R
英文名稱 CXXC5 Rabbit pAb
中文名稱 二硫鍵氧化還原酶鋅指蛋白5抗體
別    名 RINF; WID; CF5; CXXC finger protein 5; CXXC-type zinc finger protein 5; CXXC5; (Cys-Xaa-Xaa-Cys)5; CXXC5_HUMAN; HSPC195; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; retinoid-inducible nuclear factor; WT1-induced Inhibitor of Dishevelled.  
研究領域 腫瘤  細胞生物  信號轉導  干細胞  細胞周期蛋白  轉錄調節因子  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Chicken,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 24-34 kDa
檢測分子量
細胞定位 細胞核 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CXXC5: 251-322/322 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells.

Function:
May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis.

Subunit:
Interacts with DVL1 (By similarity).

Subcellular Location:
Nucleus. Cytoplasm (By similarity). Note=Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane (By similarity).

Similarity:
Contains 1 CXXC-type zinc finger.

SWISS:
Q7LFL8

Gene ID:
51523

Database links:
UniProtKB/Swiss-Prot: Q7LFL8.1

產品圖片
Sample: Cerebellum (Mouse) Lysate at 40 ug Primary: Anti- CXXC5 (bs-6890R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 24-34 kD Observed band size: 34 kD
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