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LRRC15 Rabbit pAb (bs-6815R)  
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產品編號 bs-6815R
英文名稱 LRRC15 Rabbit pAb
中文名稱 富含亮氨酸重復蛋白15抗體
別    名 Leucine-rich repeat-containing protein 15; LIB; LRC15_HUMAN.  
Specific References  (1)     |     bs-6815R has been referenced in 1 publications.
[IF=6.107] Toriumi Kensuke. et al. LRRC15 Expression Indicates High Level of Stemness Regulated by TWIST1 in Mesenchymal Stem Cells. ISCIENCE. 2022 Dec 30  FCM ;  Human, Mouse.  
研究領域 腫瘤  神經生物學  信號轉導  腫瘤細胞生物標志物  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 62 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LRRC15: 251-350/581 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 LRRC15 may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion.

Function:
LRRC15 may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential)

Tissue Specificity:
Brain and placenta.

Similarity:
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q8TF66

Gene ID:
131578

Database links:
UniProtKB/Swiss-Prot: Q8TF66.2

產品圖片
Sample: Lane 1: Mouse Placenta tissue lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Rat Placenta tissue lysates Lane 4: Rat Cerebrum tissue lysates Lane 5: Human U87MG cell lysates Lane 6: Human U-2 OS cell lysates Lane 7: Human HeLa cell lysates Primary: Anti-LRRC15 (bs-6815R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 62 kDa Observed band size: 64 kDa
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